Renal anion transport
نویسندگان
چکیده
منابع مشابه
Divalent anion transport in isolated renal tubules.
Inorganic phosphate and sulfate are the major divalent anions in biological fluids at physiological pH. The isolated perfused renal tubule technique has been used to address a number of questions about their renal transport; the purpose of this review is to summarize this information. Initial studies addressed traditional questions about the direction and segmental localization of phosphate and...
متن کاملAnion transport in heart.
Anion transport proteins in mammalian cells participate in a wide variety of cell and intracellular organelle functions, including regulation of electrical activity, pH, volume, and the transport of osmolites and metabolites, and may even play a role in the control of immunological responses, cell migration, cell proliferation, and differentiation. Although significant progress over the past de...
متن کاملAnion transport and GABA signaling
Whereas activation of GABAA receptors by GABA usually results in a hyperpolarizing influx of chloride into the neuron, the reversed chloride driving force in the immature nervous system results in a depolarizing efflux of chloride. This GABAergic depolarization is deemed to be important for the maturation of the neuronal network. The concept of a developmental GABA switch has mainly been derive...
متن کاملHuman organic anion transporters and human organic cation transporters mediate renal antiviral transport.
Renal excretion is an important elimination pathway for antiviral agents, such as acyclovir (ACV), ganciclovir (GCV), and zidovudine (AZT). The purpose of this study was to elucidate the molecular mechanisms of renal ACV, GCV, and AZT transport using cells stably expressing human organic anion transporter 1 (hOAT1), hOAT2, hOAT3, and hOAT4, and human organic cation transporter 1 (hOCT1) and hOC...
متن کاملRenal sulfate transport at the basolateral membrane is mediated by anion exchange.
The transport of sulfate was studied in basolateral membrane (BLM) vesicles isolated from rat kidney cortex by centrifugation on a Percoll self-generating gradient. In contrast to sulfate transport at the luminal membrane, sulfate uptake by BLM vesicles was not sodium dependent. However, imposition of an inside greater than outside bicarbonate gradient stimulated BLM sulfate uptake nearly 10-fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1989
ISSN: 0085-2538
DOI: 10.1038/ki.1989.207